Discovery-based science education represents a structured alternative to open-ended forms of hands-on inquiry that is now being employed in a number of secondary and post-secondary settings to address science education reform agendas. In the context of molecular life science education, this particular form of instruction links domain knowledge, laboratory methods, and bioinformatics (or computational biology) within the framework of a complete and integrated analytic workflow that culminates in a tangible scientific output and a bona fide contribution to a particular body of scientific